Publications
[23] Bioanalytic resilient nanostructured microneedle longitudinally monitors renal and hepatic drug clearance and dysfunction
Jialun Zhu, Xuanbing Cheng, Mohammadreza Bahramian, Kuanming Yao, Zongqi Li, Bintao Hu, Tsung-Yu Wu, Kiarash A. Sabet, Jiarui Cui, Jiawei Tan, Junjie Fang, Yifu Li, Connie Ho, Joshua Ng, Anthony Sung, Isabel Romero, Shuyu Lin, Yichao Zhao, Kaiji Zhang, Ryan Chaiyakul, Hanie Yousefi, Connor D. Flynn, Jagotamoy Das, David Jelinek, Laurent Voisin, Aaron Ambrus, Ao Zhang, Yitian Chi, Yu Chen, Chong Liu, Hilary A. Coller, Benjamin M. Wu, Nanthia Suthana, Shana O. Kelley, Carlos Milla, Ira Kurtz, Sam Emaminejad
Science Translational Medicine, in press.
[22] Towards Reagentless and Universal Biomolecular Sensing: Molecular Pendulum- Based Bioanalysis
Zhenwei Wu, Scott E. Isaacson, Connor D. Flynn, Jagotamoy Das, Shana O. Kelley
Accounts of Chemical Research, 2025.
[21] Wearable biomolecular sensing nanotechnologies for chronic disease management
Jiaobing Tu*, Connor D. Flynn*, Jeonghee Yeom, Zhenwei Wu, Shana O. Kelley, Wei Gao
Nature Nanotechnology, 2025.
[20] Dual-Chronoamperometry Drift Correction for Electrochemical Sensors
Kimberly Riordan, Kefan Yang, Ethan Brazelton, Mohammed Eslami, Ashley Copenhaver, Fatemeh Esmaeili, Connor D. Flynn, Zhenwei Wu, Scott E. Isaacson, Dingran Chang, Maria de Lourdes Cabezas, Vuslat Juska, Jagotamoy Das, Edward H. Sargent, Shana O. Kelley
ACS Sensors, 2025.
[19] Programming Aptamer-Protein Complexation Kinetics via Modulation of G- quadruplex Secondary Structure
Connor D. Flynn*, Dingran Chang*, Yebin Lee, Scott E. Isaacson, Zhenwei Wu, Jonathan Rivnay, Shana O. Kelley
Journal of the American Chemical Society, 2025.
[18] Continuous insulin monitoring using an antibody-protecting zwitterionic microneedle patch
Amin GhavamiNejad*, Connor D. Flynn*, Armin Geraili*, Sako Mirzaie, Fatemeh Esmaeili, Hossein Zargartalebi, Sharif Ahmed, Vuslat B Juska, Jagotamoy Das, Abdalla Abdrabou, Yi Yun Zhang, Edward H. Sargent, Shana O. Kelley
Nature Biomedical Engineering, 2025
[17] Nanobody receptors enable high-sensitivity monitoring of IL-6 using molecular pendulum bioanalysis
Connor D. Flynn*, Zhenwei Wu*, Amy Bantle, Scott E. Isaacson, Dingran Chang, Alam Mahmud, Hanie Yousefi, Jagotamoy Das, Shana O. Kelley
Analytical Chemistry, 2025
[16] Antifouling spiky nanoelectrodes enhance detection of bacterial mRNA
Yuhao Leo Wu, Jin Jia, Jagotamoy Das, Kimberly T. Riordan, Connor D. Flynn, Yi Wang, Shana O. Kelley, Teri W. Odom
Journal of the American Chemical Society, 2025
[15] Active-reset protein sensors enable continuous in vivo monitoring of inflammation
Hossein Zargartalebi, Sako Mirzaie, Amin GhavamiNejad, Sharif Ahmed, Armin Geraili, Connor D. Flynn, Dingran Chang, Jagotamoy Das, Abdalla Abdrabou, Edward H. Sargent, Shana O. Kelley
Science, 2024
[14] Highly stable biotemplated InP/ZnSe/ZnS quantum dots for in situ bacterial monitoring
Hanie Yousefi, Laxmi Kishore Sagar, Armin Geraili, Dingran Chang, F. Pelayo Garcia de Arquer, Connor D. Flynn, Seungjin Lee, Edward H. Sargent, Shana O. Kelley
ACS Applied Materials & Interfaces, 2024
[13] Spiky gold nanoparticles, a nanoscale approach to enhanced ex vivo T-cell activation
Fatemeh Esmaeili, Yuhao Leo Wu, Zongjie Wang, Abdalla Abdrabou, Vuslat B. Juska, Hossein Zargartalebi, Connor D. Flynn, Teri W. Odom, Edward H. Sargent, Shana O. Kelley
ACS Nano, 2024
[12] Self-assembled monolayer transporters enable reagentless analysis of small molecule analytes
Connor D. Flynn, Kimberly T. Riordan, Tiana L. Young, Dingran Chang, Zhenwei Wu, Scott E. Isaacson, Hanie Yousefi, Jagotamoy Das, Shana O. Kelley
ACS Sensors, 2024
[11] Artificial intelligence in point-of-care biosensing: challenges and opportunities
Connor D. Flynn, Dingran Chang
Diagnostics, 2024
[10] A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles
Kangfu Chen, Bill TV Duong, Sharif U Ahmed, Piriththiv Dhavarasa, Zongjie Wang, Mahmoud Labib, Connor D. Flynn, Jingya Xu, Yi Y Zhang, Hansen Wang, Xiaolong Yang, Jagotamoy Das, Hossein Zargartalebi, Yuan Ma, Shana O. Kelley
Nature Communications, 2023
[9] A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities
Dingran Chang, Zongjie Wang, Connor D. Flynn, Alam Mahmud, Mahmoud Labib, Hansen Wang, Armin Geraili, Xiangling Li, Jiaqi Zhang, Edward H. Sargent, Shana O. Kelley
Nature Chemistry, 2023
[8] Biomolecular sensors for advanced physiological monitoring
Connor D. Flynn, Dingran Chang, Alam Mahmud, Hanie Yousefi, Jagotamoy Das, Kimberly T. Riordan, Edward H. Sargent, Shana O. Kelley
Nature Reviews Bioengineering, 2023
[7] Monitoring cardiac biomarkers with aptamer-based molecular pendulum sensors
Alam Mahmud, Dingran Chang, Jagotamoy Das, Surath Gomis, Farid Foroutan, Jenise B Chen, Laxman Pandey, Connor D Flynn, Hanie Yousefi, Armin Geraili, Heather J Ross, Edward H Sargent, Shana O Kelley
Angewandte Chemie, 2023
[6] Electrochemical detection of Borrelia burgdorferi using a biomimetic flow cell system
Connor D. Flynn, Mariusz Sandomierski, Kelly Kim, Julie Lewis, Vett Lloyd, Anna Ignaszak
ACS Measurement Science Au, 2023
[5] Capillary-assisted molecular pendulum bioanalysis
Hossein Zargartalebi, Hanie Yousefi, Connor D. Flynn, Surath Gomis, Jagotamoy Das, Tiana L. Young, Emily Chien, Samira Mubareka, Allison McGeer, Hansen Wang, Edward H. Sargent, Amir Sanati Nezhad, Shana O. Kelley
Journal of the American Chemical Society, 2022
[4] Strategies for multiplexed electrochemical sensor development
Uroš Zupančič, Joshua Rainbow, Connor D. Flynn, Josephine Aidoo-Brown, Pedro Estrela, Despina Moschou
Modern Techniques in Biosensors: Detection Methods and Commercial Aspects, 2021
[3] Lyme disease biosensors: a potential solution to a diagnostic dilemma
Connor D. Flynn, Anna Ignaszak
Biosensors, 2019
[2] Nanostructured Cu2O synthesized via bipolar electrochemistry
Steven McWilliams, Connor D Flynn, Jennifer McWilliams, Donna C Arnold, Ruri Agung Wahyuono, Andreas Undisz, Markus Rettenmayr, Anna Ignaszak
Nanomaterials, 2019
[1] Discovery of new code interference phenomenon in GPS observables
Connor D. Flynn, Anthony M. McCaffrey, P. T. Jayachandran, Richard B. Langley
GPS Solutions, 2019